{"id":10013,"date":"2004-12-15T00:00:00","date_gmt":"2004-12-15T05:00:00","guid":{"rendered":"http:\/\/localhost\/thenewatlantis.com\/publications\/acorns-and-embryos"},"modified":"2020-09-26T16:10:00","modified_gmt":"2020-09-26T20:10:00","slug":"acorns-and-embryos","status":"publish","type":"article","link":"https:\/\/www.thenewatlantis.com\/publications\/acorns-and-embryos","title":{"rendered":"Acorns and Embryos"},"content":{"rendered":"\n<p class=\"has-drop-cap\">The prestigious <em>New England Journal of Medicine<\/em> (<em>NEJM<\/em>) recently invited two members of the President\u2019s Council on Bioethics to reflect on the ethics of using embryonic stem cells in biomedical research. Paul McHugh, a professor of psychiatry at Johns Hopkins University, explained his opposition to the destruction of human embryos created by the union of gametes, but sought to distinguish such embryos from what he dubbed \u201cclonotes\u201d: that is, embryos brought into being by cloning (a process known technically as \u201csomatic cell nuclear transfer\u201d or SCNT). He argued that human \u201cclonotes\u201d are not really human embryos, and thus do not enjoy the high moral status of embryos brought into being by ordinary sexual intercourse or by the process of in vitro fertilization (IVF). These \u201cclonotes,\u201d McHugh argued, may be legitimately destroyed for purposes of stem cell harvesting, so long as they are destroyed before the fourteenth day of their development. Michael Sandel, a professor of political theory at Harvard University, defended the killing of human embryos in biomedical research without regard to the method by which such embryos are brought into being. In his view, human embryos, whether produced by union of sperm and egg or by somatic cell nuclear transfer, are not entitled to the moral immunity against direct attack that is enjoyed by human beings at later developmental stages.<\/p>\n\n\n\n<p>Both McHugh and Sandel are leading figures in the embryo research debate, and the arguments they put forward are made frequently by others seeking moral grounds for engaging in the destruction of human embryos. But these arguments do not withstand critical examination. In our view, human beings in the embryonic stage are entitled to the same immunity from attack that is enjoyed by human beings at later developmental stages, and it is irrelevant whether these embryonic human beings came into existence by sexual union, in vitro fertilization, or somatic cell nuclear transfer.<\/p>\n\n\n<div class=\"lazyblock-section-break-ZsdpDq wp-block-lazyblock-section-break\"><div class=\"block-tna-section-break mt-12 pt-2 mb-6\">\r\n  <div class=\"mb-12 pb-2 flex justify-center\">\r\n    <svg class=\"fill-current\" height=\"1\" width=\"91\" viewBox=\"0 0 91 1\">\r\n      <path d=\"M91 .5L62.706 1H28.447L0 .5 28.447 0h34.259L91 .5z\"\/>\r\n    <\/svg>\r\n  <\/div>\r\n\t<h5 class=\"leading-none font-callunasans font-bold text-center text-almost-black text-lg\">\r\n\t\tThe Basic Dispute\t<\/h5>\r\n<\/div><\/div>\n\n\n<p class=\"has-drop-cap\">Part of the problem we face is the way the issue has been framed by the editors of the <em>New England Journal of Medicine<\/em> and many others who have waded into the debate. Absent the appropriate framing of the issue, there is little likelihood of generating an illuminating public discussion.<\/p>\n\n\n\n<p>If we were to contemplate killing mentally retarded infants to obtain transplantable organs, no one would characterize the resulting controversy as a debate \u201cabout organ transplantation.\u201d The dispute would properly be characterized as a debate about the ethics of killing retarded children to harvest their vital organs. The issue could not be resolved by considering how many gravely ill non-retarded people could be saved by extracting a heart, two kidneys, and a liver from each retarded child. The threshold question would be whether it is unjust to relegate a certain class of human beings \u2014 the retarded \u2014 to the status of objects that can be killed and dissected to benefit others.<\/p>\n\n\n\n<p>By the same token, we should not be speaking in terms of a debate \u201cabout embryonic stem cell research.\u201d No one would object to the use of embryonic stem cells in biomedical research or therapy if they could be harvested without killing or harming the embryos from whom they were obtained. Nor would anyone object to using such cells if they could be obtained from embryos lost in spontaneous abortions. The point of controversy is the ethics of deliberately destroying human embryos for the purpose of harvesting their stem cells. The threshold question is whether it is unjust to kill members of a certain class of human beings \u2014 those in the embryonic stage of development \u2014 to benefit others.<\/p>\n\n\n\n<p>But are human embryos human beings?<\/p>\n\n\n\n<p>Indeed they are, and contemporary human embryology and developmental biology leave no significant room for doubt about it. The adult human being reading these words was, at an earlier stage of his or her life, an adolescent, and before that an infant. At still earlier stages he or she was a fetus and before that an embryo. In the infant, fetal, and embryonic stages, each of us was then what we are now, namely, a whole living member of the species <em>Homo sapiens<\/em>. Each of us developed by a gradual, unified, and self-directed process from the embryonic into and through the fetal, infant, child, and adolescent stages of human development, and into adulthood, with his or her determinateness, unity, and identity fully intact. Although none of us was ever a sperm cell or an ovum \u2014 the sperm and ovum from whose union we emerged were genetically and functionally parts of other human beings \u2014 each of us was once an embryo, just as we were once infants, children, and adolescents. In referring to \u201cthe embryo,\u201d then, we are referring not to something distinct from the human being that each of us is, but rather to a certain stage in the development of each human being \u2014 like saying \u201cthe teenager\u201d or \u201cthe five-year old.\u201d<\/p>\n\n\n\n<p>Some scientists and philosophers who agree with us about the status of human embryos as human beings nevertheless believe (mistakenly, in our view) that killing embryos in biomedical research can be justified. Some defend embryo-killing on utilitarian grounds, by asserting that killing a few thousand embryos today will help millions of suffering patients in the future. Others argue that no wrong is done in destroying \u201cspare\u201d IVF embryos that would otherwise be permanently frozen or discarded. There are, however, scholars who are prepared to deny that human embryos are human beings. Michael Sandel does just that in his <em>NEJM<\/em> article. He defends embryo-killing in biomedical research on the ground that human embryos and human beings are different <em>kinds<\/em> of entities.<\/p>\n\n\n<div class=\"lazyblock-section-break-2mKoGj wp-block-lazyblock-section-break\"><div class=\"block-tna-section-break mt-12 pt-2 mb-6\">\r\n  <div class=\"mb-12 pb-2 flex justify-center\">\r\n    <svg class=\"fill-current\" height=\"1\" width=\"91\" viewBox=\"0 0 91 1\">\r\n      <path d=\"M91 .5L62.706 1H28.447L0 .5 28.447 0h34.259L91 .5z\"\/>\r\n    <\/svg>\r\n  <\/div>\r\n\t<h5 class=\"leading-none font-callunasans font-bold text-center text-almost-black text-lg\">\r\n\t\tA Difference in Kind?\t<\/h5>\r\n<\/div><\/div>\n\n\n<p class=\"has-drop-cap\">At the core of Sandel\u2019s argument is an analogy:<\/p>\n\n\n\n<blockquote class=\"wp-block-quote\"><p>although every oak tree was once an acorn, it does not follow that acorns are oak trees, or that I should treat the loss of an acorn eaten by a squirrel in my front yard as the same kind of loss as the death of an oak tree felled by a storm. Despite their developmental continuity, acorns and oak trees are different kinds of things.<\/p><\/blockquote>\n\n\n\n<p>Sandel maintains that, by analogy, embryos are different in <em>kind<\/em> from human beings. But this argument cannot survive scrutiny.<\/p>\n\n\n\n<p>As Sandel himself implicitly concedes, <em>we value human beings precisely because of the kind of entities they are<\/em>. (That is why he has staked his entire argument on the proposition that human embryos are different <em>in kind <\/em>from human beings.) Indeed, that is why we consider all human beings to be equal in basic dignity and human rights. By contrast, we value oak trees because of certain accidental attributes they have, such as their magnificence, their special beauty, or a certain grandeur that has taken perhaps seventy-five or a hundred years to achieve. If oak trees <em>were<\/em> valuable in virtue of the <em>kind<\/em> of entity they are, then it <em>would<\/em> follow that it is just as unfortunate to lose an acorn as an oak tree (though our emotional reaction to the two different kinds of loss might, for a variety of possible reasons, nevertheless differ). Sandel\u2019s purported analogy works only if he disregards the key proposition asserted by opponents of embryo-killing: that all human beings, irrespective of age, size, stage of development, or condition of dependency, possess equal and intrinsic dignity by virtue of <em>what<\/em> (i.e., <em>the kind<\/em> of entity) they are, not in virtue of any accidental characteristics, which can come and go, and which are present in human beings in varying degrees. Oak trees and acorns are not equally valuable, because the basis for their value is not <em>what<\/em> they are but precisely those accidental characteristics by which oak trees differ from acorns. We value the ugly, decaying oak tree less than the magnificent, still flourishing one; and we value the mature, magnificent oak more than the small, still growing one. But we would never say the same about human beings.<\/p>\n\n\n\n<p>Sandel\u2019s argument begins to go awry with his choice of analogates. The acorn is analogous to the embryo and the oak tree (he says) is analogous to the \u201chuman being.\u201d But in view of the developmental continuity that Sandel rightly concedes, surely the proper analogate of the oak tree is the mature human being, i.e., <em>the adult<\/em>. Of course, Sandel\u2019s analogy has its force because we really do feel a sense of loss when a <em>mature<\/em> oak is felled. But while it is true that we do not feel the same sense of loss at the destruction of an acorn, <em>it is also true that we do not feel the same sense of loss at the destruction of an oak sapling<\/em>. (Indeed, our reaction to the destruction of a sapling is much more like our reaction to the destruction of an acorn than it is like our reaction to the destruction of a mature oak.) But clearly the oak tree does not differ <em>in kind<\/em> from the oak sapling. This shows that we value oak trees not because of the kind of entity they are, but rather because of their magnificence. Neither acorns nor saplings are magnificent, so we do not experience a sense of loss when they are destroyed.<\/p>\n\n\n\n<p>But the basis for our valuing human beings is profoundly different. We do not believe that especially magnificent human beings \u2014 such as Michael Jordan or Albert Einstein \u2014 are of greater inherent worth and dignity than human beings who are physically frail or mentally impaired. We would not tolerate the killing of a retarded child or a person suffering from, say, brain cancer in order to harvest transplantable organs to save Jordan or Einstein.<\/p>\n\n\n\n<p>And we do not tolerate the killing of infants, which on Sandel\u2019s analogy would be analogous to the oak saplings at whose destruction we feel no particular sense of loss. Managers of oak forests freely kill saplings, just as they might destroy acorns, to ensure the health of the more mature trees. No one regrets this, or gives it a second thought. This is precisely because we do not value members of the oak species \u2014 as we value human beings \u2014 because of the kind of entity they are. If we did value oaks for the kind of entity they are, and not for their magnificence, then we would likely feel a sense of loss at the destruction of saplings, and it would be reasonable to feel a similar sense of loss at the destruction of acorns. Conversely, if we valued human beings in a way analogous to that in which we value oak trees, then we would have no reason to object to killing human infants or even mature human beings who were severely \u201cdefective.\u201d<\/p>\n\n\n\n<p>In sum, Sandel\u2019s defense of embryo-killing on the basis of an analogy between embryos and acorns collapses the moment one brings into focus the profound difference between the basis on which we value oak trees and the basis on which we ascribe intrinsic value and dignity to human beings. His analogy only makes sense if we reject the principle that all human beings possess equal moral worth \u2014 a principle that we assume Sandel wishes to uphold, not reject.<\/p>\n\n\n<div class=\"lazyblock-section-break-ESCTz wp-block-lazyblock-section-break\"><div class=\"block-tna-section-break mt-12 pt-2 mb-6\">\r\n  <div class=\"mb-12 pb-2 flex justify-center\">\r\n    <svg class=\"fill-current\" height=\"1\" width=\"91\" viewBox=\"0 0 91 1\">\r\n      <path d=\"M91 .5L62.706 1H28.447L0 .5 28.447 0h34.259L91 .5z\"\/>\r\n    <\/svg>\r\n  <\/div>\r\n\t<h5 class=\"leading-none font-callunasans font-bold text-center text-almost-black text-lg\">\r\n\t\tTaking Continuity Seriously\t<\/h5>\r\n<\/div><\/div>\n\n\n<p class=\"has-drop-cap\">Sandel\u2019s argument also relies on an equivocation of the terms \u201coak tree\u201d and \u201chuman being.\u201d Of course, as Sandel says, acorns are not oak trees \u2014 <em>if<\/em> by \u201coak tree\u201d one means a <em>mature<\/em> member of the oak species. By the same token, a sapling is not an \u201coak tree\u201d if <em>that<\/em> is what one means (nor, by the same reasoning, is an infant a human being). But if by \u201coak tree\u201d (or \u201coak\u201d) one means simply any member of the <em>species<\/em>, then an acorn (or a sapling) <em>is<\/em> an oak tree \u2014 they are identical <em>substances<\/em>, differing only in maturity or stage of natural development.<\/p>\n\n\n\n<p>Similarly, no one claims that embryos are <em>mature<\/em> human beings, that is, adults. But human embryos <em>are<\/em> human beings, that is, complete, though immature, members of the human species. Embryos are human individuals at an early stage of their development, just as adolescents, toddlers, infants, and fetuses are human individuals at various developmental stages. So to say, as Sandel does, that embryos and human beings are different <em>kinds<\/em> of things is true only if one focuses exclusively on the accidental characteristics \u2014 size, degree of development, and so on. But the central question is, precisely, should we focus only on the accidental characteristics by which embryonic human beings differ from mature human beings, or should we recognize their essential nature (that is, <em>what they are<\/em>)?<\/p>\n\n\n\n<p>Sandel\u2019s claim that human embryos are not human beings, or not \u201cfull human beings,\u201d or merely \u201cpotential human life,\u201d simply cannot be squared with the facts of human embryogenesis and developmental biology. Briefly, modern embryology shows the following: (1) The embryo is from the start <em>distinct<\/em> from any cell of the mother or the father, for it is growing in its own distinct direction and its growth is internally directed to its own survival and maturation. (2) The embryo is <em>human<\/em>, since it has the genetic constitution and epigenetic primordia characteristic of human beings. (3) Most importantly, the embryo is a <em>complete<\/em> or <em>whole<\/em> organism, though immature. From conception onward, the human embryo is fully programmed, and has the active disposition, to develop himself or herself to the next mature stage of a human being. And unless prevented by disease, violence, or a hostile environment, the embryo will actually do so, despite possibly significant variation in its circumstances (i.e., in the mother\u2019s womb). None of the changes that occur to the embryo after fertilization, for as long as he or she survives, generates a new direction of growth. Rather, <em>all<\/em> of the changes (for example those involving nutrition and environment) either facilitate or retard the internally directed growth of this persisting individual.<\/p>\n\n\n<div class=\"lazyblock-section-break-Z13Dfs7 wp-block-lazyblock-section-break\"><div class=\"block-tna-section-break mt-12 pt-2 mb-6\">\r\n  <div class=\"mb-12 pb-2 flex justify-center\">\r\n    <svg class=\"fill-current\" height=\"1\" width=\"91\" viewBox=\"0 0 91 1\">\r\n      <path d=\"M91 .5L62.706 1H28.447L0 .5 28.447 0h34.259L91 .5z\"\/>\r\n    <\/svg>\r\n  <\/div>\r\n\t<h5 class=\"leading-none font-callunasans font-bold text-center text-almost-black text-lg\">\r\n\t\tThe Nature of Persons\t<\/h5>\r\n<\/div><\/div>\n\n\n<p class=\"has-drop-cap\">Perhaps with these facts in mind, Sandel sometimes seems to consider that though human embryos are human beings as a matter of biological fact (for example, he says that an oak tree was once an acorn, which, by analogy, would mean that more mature human beings were once embryos), they are not <em>persons<\/em>. According to this position, which has been famously promoted by Peter Singer and Ronald Dworkin, although we were once human embryos, we were not persons at that time and were not entitled to the respect and protection against lethal violence due to persons. And when did we become persons? Sandel, like Singer and Dworkin, says that the important difference between human embryos and human persons is that persons are not only sentient but \u201ccapable of experience and consciousness,\u201d and therefore \u201cmake higher claims\u201d on us than beings who lack such capacities.<\/p>\n\n\n\n<p>But personhood is <em>not<\/em> an accidental characteristic, that is, a characteristic which one acquires at some point after he exists and may lose at another point. One is a human person by being a living member of the human community, a member of the human species. It is true that many people cannot immediately exercise the rational capacities characteristic of members of the species \u2014 such as the elderly person with dementia whose rational powers are gone forever, or the comatose person whose rational powers may or may not return, or infants, fetuses, and embryos whose rational powers are still developing. But such individuals are still morally valuable persons, at least to those who value all human beings equally. They are still members of the human community. Being a person is not a result of acquired accidental attributes; rather, it is being a certain type of individual, an individual with a rational <em>nature<\/em>. And human beings are individuals with a rational nature at every stage of their existence. We come into being as individuals with a rational nature, and we do not cease being such individuals until we cease to be (by dying). We did not acquire a rational nature by achieving sentience or the immediately exercisable capacity for rational inquiry and deliberation. We were individuals with a rational nature even during the early childhood, infant, fetal, and embryonic stages of our lives. If we are persons <em>now<\/em>, we were persons <em>then<\/em>. We were never \u201chuman nonpersons.\u201d<\/p>\n\n\n<div class=\"lazyblock-section-break-Z1wBor7 wp-block-lazyblock-section-break\"><div class=\"block-tna-section-break mt-12 pt-2 mb-6\">\r\n  <div class=\"mb-12 pb-2 flex justify-center\">\r\n    <svg class=\"fill-current\" height=\"1\" width=\"91\" viewBox=\"0 0 91 1\">\r\n      <path d=\"M91 .5L62.706 1H28.447L0 .5 28.447 0h34.259L91 .5z\"\/>\r\n    <\/svg>\r\n  <\/div>\r\n\t<h5 class=\"leading-none font-callunasans font-bold text-center text-almost-black text-lg\">\r\n\t\tThe Implications of Equality\t<\/h5>\r\n<\/div><\/div>\n\n\n<p class=\"has-drop-cap\">Sandel\u2019s final argument is that holding that a human embryo is a person has logical implications that either no one accepts or that are simply unacceptable. Those who hold that human embryos are persons, Sandel says, should be in favor of a total ban on the destruction of human embryos for research, not just a prohibition on federal funding. And they should be opposed to any fertility treatments that involve the creation and discarding of \u201cexcess\u201d embryos. To this we reply that we <em>are<\/em> opposed to those practices \u2014 we are opposed to <em>all<\/em> dissecting or deliberate discarding of living human embryos. It is worth pointing out, though, that federal funding for the killing or discarding of human embryos (the matter now being debated) is worse than the failure to provide equal protection of the law to a class of human beings (the larger issue). If the government funds embryo destruction, then it is forcing us to participate, as members of the political community, in the killing of human beings. And while we would surely support a national ban on the deliberate destruction of any human embryo, we also seek to uphold those limits that can be preserved at present, while making the fundamental moral arguments about why additional limits are needed, and why other promising areas of research (like adult stem cells) should be pursued as morally desirable alternatives. It is better to prohibit the federal funding of embryo destruction than to prohibit nothing at all, even if it would be better still to prohibit the act of embryo destruction itself.<\/p>\n\n\n\n<p>Sandel also points to the frequent occurrence of early spontaneous abortions, claiming that \u201cmore than half of all fertilized eggs either fail to implant or are otherwise lost.\u201d He then says that \u201cthe way we respond to the natural loss of embryos suggests that we do not regard this event as the moral or religious equivalent of the death of infants.\u201d There are, he points out, few burial rituals or mourning rites for the loss of an embryo. As a factual matter, Sandel somewhat exaggerates the rate of early pregnancy loss, with leading embryologists estimating a loss rate of roughly 45 to 50 percent. Moreover, as almost all authorities in human embryology note, many of these unsuccessful pregnancies are really due to incomplete or defective fertilizations, and so in many cases, what is lost is not actually a human embryo. (To be a complete human organism, a human being, the entity must have the epigenetic primordia for a functioning brain and nervous system, which may be lacking as a result of a severe chromosomal defect.) But even if Sandel had the facts right, his argument here does not hold up. The absence of formal burial rites and (in many cases) intense mourning for the embryo who dies is explained by numerous considerations having nothing to do with whether human beings in the embryonic stage of development possess human dignity or intrinsic worth. Chief among these is the fact that people have not had the opportunity to bond emotionally with the human being who is lost at an early stage of development. As to the way we respond to miscarriages, Sandel is mistaken to assume it is uniform. Many people, women in particular, very often <em>do<\/em> grieve intensely when a miscarriage occurs, even when it is early in pregnancy.<\/p>\n\n\n\n<p>In any event, someone\u2019s status as a human being possessing dignity and intrinsic worth in no way depends on whether anyone would grieve for him or her after death. Emotional responses are notoriously limited in their capacity to function as sources of moral knowledge. The real question is whether human embryos are human beings, as we contend, or whether they are different <em>in kind<\/em> from human beings, as Sandel attempts to show by his analogy with acorns and oak trees. His argument succeeds only if the analogy holds. But the analogy fails dramatically. The dignity of human beings is <em>intrinsic<\/em> to the kind of entity we are; it does not depend on accidental attributes like size, skin color, age, or IQ. The value we accord to oak trees is <em>conditional<\/em>; it depends precisely on those accidental attributes, like size and beauty, that make some oaks more remarkable and thus more valuable than others. And so we object to killing human infants (though we experience no great feeling of loss at the destruction of saplings), and we should object to killing human embryos (though we feel no sense of loss at the trampling of acorns).<\/p>\n\n\n<div class=\"lazyblock-section-break-1azvJN wp-block-lazyblock-section-break\"><div class=\"block-tna-section-break mt-12 pt-2 mb-6\">\r\n  <div class=\"mb-12 pb-2 flex justify-center\">\r\n    <svg class=\"fill-current\" height=\"1\" width=\"91\" viewBox=\"0 0 91 1\">\r\n      <path d=\"M91 .5L62.706 1H28.447L0 .5 28.447 0h34.259L91 .5z\"\/>\r\n    <\/svg>\r\n  <\/div>\r\n\t<h5 class=\"leading-none font-callunasans font-bold text-center text-almost-black text-lg\">\r\n\t\tThe Clonote and the Sheep\t<\/h5>\r\n<\/div><\/div>\n\n\n<p class=\"has-drop-cap\">But what about the claims of Paul McHugh? Is there a morally relevant difference between blastocysts that come into being by the union of gametes and those that are produced by somatic cell nuclear transfer? Even if human embryos are nothing other than embryonic human beings, as we argue and McHugh agrees, are \u201cclonotes\u201d something other than human embryos?<\/p>\n\n\n\n<p>Here is McHugh\u2019s argument in his own words:<\/p>\n\n\n\n<blockquote class=\"wp-block-quote\"><p>I argue that in vitro fertilization entails the begetting of a new human being right from its start as a zygote and that we should use it to produce babies rather than cells or tissues to be harvested for purposes dictated by other human beings. In contrast, SCNT is a biologic manufacturing process that we may use to produce cells but should not use to produce babies.<\/p><\/blockquote>\n\n\n\n<p>The trouble with this argument is that the \u201ccells\u201d he seeks from SCNT are derived by creating and destroying a cloned human embryo. And the \u201cclonote\u201d and the embryo, despite the different processes by which they come into being, are indistinguishable in their essential nature. What McHugh rightly says about the in vitro fertilization process, namely, that it \u201ccreates a new human being right from its start as a zygote,\u201d is also true of the entity produced by somatic cell nuclear transfer. All the biological characteristics of the embryo are to be found in the \u201cclonote.\u201d Indeed, there is no point in inventing a new word. As the vast majority of people on both sides of the ethical debate understand perfectly well, what somatic cell nuclear transfer produces is a cloned <em>embryo<\/em>.<\/p>\n\n\n\n<p>McHugh says that his \u201cdistinction rests on the origin of cells in SCNT, not on the process\u2019s vaunted potential for producing a living replica (clone) of the donor, as with Dolly the sheep.\u201d But, of course, Dolly the sheep began her life as an embryonic sheep. She did not skip the embryonic stage. In this respect, she was indistinguishable from other sheep. Similarly, a human adult brought into existence by somatic cell nuclear transfer would begin his life as a human embryo. The potential he fulfilled \u2014 namely, the potential to develop from the embryonic into and through the fetal, infant, child, and adolescent stages, and into adulthood \u2014 would be the potential he possessed from the embryonic stage forward. (Indeed, it is inaccurate to say that the embryonic Dolly had the \u201cpotential\u201d to be a living replica of the sheep from which she was cloned. From the embryonic stage forward she <em>was<\/em> a living replica of that sheep.) Just as the life of a new human being conceived by sexual union develops by a gradual and gapless process during which the developing human never changes from one kind of entity into another, so too the life of a human being produced by somatic cell nuclear transfer would unfold without what philosophers call \u201csubstantial change\u201d (i.e., a change from one kind of entity into another). In the life of such a being, there would be no point from the embryonic stage forward at which one could say that the developing being changed from a nonhuman entity into a human being. From the point at which SCNT succeeded in producing a distinct, self-integrating organism, a new human being existed.<\/p>\n\n\n\n<p>McHugh attempts to support his position with an argument in the form of a <em>reductio ad absurdum<\/em>: \u201cif one used the notion of \u2018potential\u2019 to protect cells developed through SCNT because with further manipulation they might become a living clone, then every somatic cell would deserve some protection because it has the potential to follow the same path.\u201d But this argument fails. Somatic cells that may be used in cloning are analogous not to embryos, but to gametes. Functionally, they are parts of other human beings. They are not distinct, complete, self-integrating organisms. They are not living members of the species <em>Homo sapiens<\/em>. Embryos \u2014 however produced \u2014 are.<\/p>\n\n\n\n<p>In fact, McHugh\u2019s own argument is vulnerable to a <em>reductio ad absurdum<\/em>: if a \u201cclonote\u201d is not an embryonic member of the species of the animal from which it is cloned, then even in the adult stage the cloned entity cannot be a member of that species. By this reasoning, Dolly was in fact <em>not<\/em> a sheep, and the child, and later adult, who began life as a \u201cclonote\u201d would <em>not<\/em> be a human being. But that is absurd.<\/p>\n\n\n\n<p>McHugh has one more argument. Relying on testimony given by Rudolf Jaenisch at the July 24, 2003 meeting of the President\u2019s Council on Bioethics, McHugh asserts that \u201cSCNT performed with primate cells produces embryos with such severe epigenetic problems that they cannot survive to birth.\u201d The first thing to notice about this assertion is that it concedes that the entities produced by SCNT are, in fact, embryos, albeit severely disabled ones. More importantly, Jaenisch\u2019s testimony does nothing to prove that disabled or \u201cdefective\u201d embryos lack moral worth. As we mentioned above, in some cases reproduction fails because fertilization is incomplete, and in such a case there is a growth (for example, a complete hydatidiform mole) but there is not a human embryo. But if SCNT is successful then it generates a distinct organism with the full genetic program and active disposition to develop itself in accord with that program (even if it also has a defect which will cause its early death). There are newborn infants who, as a result of genetic diseases, are destined to die in a matter of days or even hours. This fact does not alter their status as human beings. It would be scandalous to suppose that it authorizes us to treat afflicted children as impersonal collections of organs available for transplantation and research.<\/p>\n\n\n\n<p>Human beings may be severely afflicted at any developmental stage, from the embryonic to the adult. All of us will eventually die, and many of us will die as a result of factors in our genetic makeup from the point at which we came into being. From the moral viewpoint, the certainty of death \u2014 whether in ninety years or nine minutes \u2014 does not alter our inherent dignity or relieve others of the obligation to respect our lives. That someone will soon die, no matter what we do, is never a license for killing him. That the human being whose death is imminent happens to be at an earlier rather than later stage of development is morally irrelevant. Cloned human embryos are still embryonic human beings, and the fact that this particular way of initiating human life (SCNT) might harm human life does not give us a license to destroy cloned embryos or a reason to pretend that these living organisms are mere artifacts.<\/p>\n\n\n<div class=\"lazyblock-section-break-Z2fG69R wp-block-lazyblock-section-break\"><div class=\"block-tna-section-break mt-12 pt-2 mb-6\">\r\n  <div class=\"mb-12 pb-2 flex justify-center\">\r\n    <svg class=\"fill-current\" height=\"1\" width=\"91\" viewBox=\"0 0 91 1\">\r\n      <path d=\"M91 .5L62.706 1H28.447L0 .5 28.447 0h34.259L91 .5z\"\/>\r\n    <\/svg>\r\n  <\/div>\r\n\t<h5 class=\"leading-none font-callunasans font-bold text-center text-almost-black text-lg\">\r\n\t\tMoral Norms and Modern Medicine\t<\/h5>\r\n<\/div><\/div>\n\n\n<p class=\"has-drop-cap\">Like Michael Sandel and Paul McHugh, we desire to see biomedical science advance towards therapies and cures for diseases. Our objection is not to embryonic stem cell research as such, but to the killing of embryonic human beings to harvest their stem cells. We support research using stem cells that can be obtained harmlessly from bone marrow, fat, and other non-embryonic sources. The day may well come \u2014 and come soon \u2014 when it is possible to obtain embryonic stem cells without killing embryos. It is likely that at some point in the future scientists will be able to reprogam adult cells back to the embryonic stage. Even sooner, it may be possible to create non-embryonic entities, analogous to complete hydatidiform moles and teratomas, from which embryonic-type stem cells may be obtained. When that day comes, we will enthusiastically support research using these cells. Now and always, though, we believe that biomedical science must remain faithful to the moral norm against killing in the cause of healing. To fail in fidelity to this norm is to undermine the moral foundations of the very enterprise of biomedical science. We must not allow our desire for scientific advancements, and even for therapies and cures, to cloud our judgments as to what human embryos are and what it means for us deliberately to kill them.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Robert P. George and Patrick Lee on moral standing and bad metaphors<\/p>\n","protected":false},"author":1,"featured_media":18425,"template":"","article_type":[13],"noteworthy_people":[],"topics":[2291,5011],"_links":{"self":[{"href":"https:\/\/www.thenewatlantis.com\/wp-json\/wp\/v2\/article\/10013"}],"collection":[{"href":"https:\/\/www.thenewatlantis.com\/wp-json\/wp\/v2\/article"}],"about":[{"href":"https:\/\/www.thenewatlantis.com\/wp-json\/wp\/v2\/types\/article"}],"author":[{"embeddable":true,"href":"https:\/\/www.thenewatlantis.com\/wp-json\/wp\/v2\/users\/1"}],"version-history":[{"count":0,"href":"https:\/\/www.thenewatlantis.com\/wp-json\/wp\/v2\/article\/10013\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.thenewatlantis.com\/wp-json\/wp\/v2\/media\/18425"}],"wp:attachment":[{"href":"https:\/\/www.thenewatlantis.com\/wp-json\/wp\/v2\/media?parent=10013"}],"wp:term":[{"taxonomy":"article_type","embeddable":true,"href":"https:\/\/www.thenewatlantis.com\/wp-json\/wp\/v2\/article_type?post=10013"},{"taxonomy":"noteworthy_people","embeddable":true,"href":"https:\/\/www.thenewatlantis.com\/wp-json\/wp\/v2\/noteworthy_people?post=10013"},{"taxonomy":"topics","embeddable":true,"href":"https:\/\/www.thenewatlantis.com\/wp-json\/wp\/v2\/topics?post=10013"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}